The Fountain of Youth - Have we Found the Chemical Basis of Aging, and a means for its reversal? Researcher David Sinclair from University of New South Wales has identified the role of NAD in DNA repair in the human body. As we age, the protein DBC1 interferes with the proteins that repair our DNA naturally. NAD interferes with DBC1 activity, thereby enabling our natural DNA repair facility to function, but NAD production declines with age. The chemical NMN stimulates the body's natural production of NAD, and, when fed to aged mice, allowed their bodies to regenerate as though in their prime (muscles, hair, strength, agility, speed, endurance). Human trials are pending, with some individuals taking NMN supplementation voluntarily.

This discovery in mice trials is the highest profile advance in the science of age-reversal, in 2017, with implications for human disease prevention, anti-aging, and the search for extension of human life.

Review Article:
http://longevityfacts.com/nmn-nad-nicotinamide-mononucleotide-david-sinclair-interview-anti-aging-drug-trials-nicotinamide-adenine-dinucleotide-sirtuins/

Popular Science Articles
Harvard Magazine, Oct 2017, David Sinclair, Anti-Aging Approaches
https://harvardmagazine.com/2017/09/anti-aging-breakthrough

Time Magazine, Feb 2018, Is the Anti-Aging Pill on the Horizon?
http://time.com/5159879/is-an-anti-aging-pill-on-the-horizon/

Harvard Medical School, March 2018,
https://hms.harvard.edu/news/rewinding-clock

Science Daily, March 2017
https://www.sciencedaily.com/releases/2017/03/170323141340.htm


Research Publications:
March 2018, Therapeutic potential of NAD-boosting molecules, in Cell Metabolism
https://www.cell.com/cell-metabolism/abstract/S1550-4131(18)30122-0